Table 3:

DTI group results and Mann-Whitney–Wilcoxon test for comparison of mean FA with healthy controls (group Ib)*

FAPyramidPonsPeduncleCapsuleCent. Semi.Precent. Gyr.FA CSTMD CST
Group IV
    MWW(P = .062)(P = .001)(P = .001)(P < .001)(P > .05)(P > .05)
Group III
    MWW(P > .05)(P = .022)(P < .001)(P = .116)(P > .05)(P > .05)
Group II
Group Ib (controls)
  • Note:—MWW indicates Mann-Whitney–Wilcoxon test; Cent. Semi., centrum semiovale; Precent. Gyr., precentral gyrus; DTI, diffusion tensor imaging; FA, fractional anisotropy.

  • * The lowest mean FA in comparison with controls is found in the internal capsule, centrum semiovale, and the precentral gyrus of group IV (EE clinically probable/definite) and the internal capsule and centrum semiovale for patients of group III (EE clinically possible). The rightmost FA/MD CST columns illustrate diffusion characteristics averaged for the entire CST. FA ranges from 1000 (maximum anisotropy) to 0 (no anisotropy). MD exhibits statistically significant differences with elevation in the internal capsule in group IV compared with healthy controls (data not shown).