Cerebral blood flow and metabolism in the normal and increased OEF groups
| Normal OEF (n = 9) | Increased OEF (n = 4) | |
|---|---|---|
| Ipsilateral MCA | ||
| CBF (mL · 100 g−1 · min−1) | 42.6 ± 8.1 | 40.9 ± 8.1 |
| OEF (%) | 43.1 ± 3.9 | 53.7 ± 3.1 |
| CBV (mL · 100 g−1)* | 4.3 ± 1.3 | 6.3 ± 1.4 |
| CMRO2 (mL · 100 g−1 · min−1) | 3.3 ± 0.6 | 3.4 ± 0.5 |
| CBF/CBV (min−1)* | 10.5 ± 2.9 | 6.6 ± 1.2 |
| Ipsilateral corona radiata | ||
| CBF | 30.6 ± 9.2 | 28.9 ± 4.9 |
| OEF | 39.2 ± 7.7 | 46.8 ± 5.5 |
| CBV* | 3.1 ± 1.3 | 5.0 ± 0.7 |
| CMRO2 | 2.1 ± 0.5 | 2.1 ± 0.3 |
| CBF/CBV* | 11.5 ± 6.0 | 6.0 ± 1.5 |
| Contralateral MCA | ||
| CBF | 46.8 ± 5.7 | 42.7 ± 11.4 |
| OEF† | 41.8 ± 3.9 | 50.0 ± 4.3 |
| CBV | 4.3 ± 1.2 | 5.5 ± 1.6 |
| CMRO2 | 3.5 ± 0.5 | 3.3 ± 0.7 |
| CBF/CBV | 11.6 ± 3.3 | 8.4 ± 3.9 |
| Ipsilateral ACA | ||
| CBF | 41.3 ± 6.2 | 36.0 ± 8.9 |
| OEF† | 40.8 ± 3.8 | 50.4 ± 5.7 |
| CBV | 4.6 ± 1.4 | 5.5 ± 1.2 |
| CMRO2 | 3.0 ± 0.3 | 2.8 ± 0.6 |
| CBF/CBV | 10.0 ± 4.1 | 6.7 ± 2.0 |
| Ipsilateral PCA | ||
| CBF | 43.8 ± 8.3 | 41.0 ± 7.2 |
| OEF† | 44.3 ± 4.2 | 53.5 ± 4.4 |
| CBV | 4.4 ± 1.5 | 6.3 ± 1.7 |
| CMRO2 | 3.2 ± 0.5 | 3.4 ± 0.6 |
| CBF/CBV | 10.0 ± 3.4 | 6.7 ± 1.2 |
Note:—CBF indicates cerebral bloodflow; OEF, oxygen extraction fraction; CBV, cerebral blood volume; CMRO2, cerebral metabolic rate of oxygen; MCA, middle cerebral artery; ACA, anterior cerebral artery; PCA, posterior cerebral artery.
* P < .05.
† P < .01.