Univariate statistics of angiographic results and methods of LIT-MCD for patients with poor clinical outcome and favorable outcome
| Clinical Outcome at 90 Days | P | ||
|---|---|---|---|
| Poor (mRS, 3–6) | Favorable (mRS, 0–2) | ||
| No. of patients | 42 | 48 | |
| Location of occlusion | |||
| Proximal M1a | 17 (41%) | 3 (6%) | <.001b |
| Distal M1 | 12 (29%) | 17 (35%) | .488b |
| M2c | 13 (31%) | 28 (58%) | .009b |
| No. of patients with | |||
| Preprocedural TICI of grade 0 | 38 (90%) | 37 (77%) | .089b |
| Poor collaterals (CFGS, grade 1) | 6 (14%) | 2 (4%) | .139d |
| Moderate collaterals (grade 2) | 35 (83%) | 41 (85%) | .786b |
| Ample collaterals (grade 3) | 1 (2%) | 5 (10%) | .209d |
| Dose of urokinase (×103 U) (mean) | 237 ± 9.1 | 265 ± 10.0 | .172e |
| Use of low dose of urokinase (≤240,000 U) | 37 (88%) | 33 (69%) | .028b |
| Use of mechanical clot disruption | 37 (88%) | 25 (52%) | <.001b |
| No recanalization (TICI grade 0 + 1) | 15 (36%) | 2 (4%) | <.001b |
| Postprocedural TICI grade | |||
| 0 | 12 (29%) | 1 (2%) | <.001b |
| 1 | 3 (7%) | 1 (2%) | .336d |
| 2a | 18 (43%) | 19 (40%) | .753b |
| 2b | 7 (17%) | 16 (33%) | .071b |
| 3 | 2 (5%) | 11 (23%) | .015b |
| Procedure-related complications | 5 (12%) | 4 (8%) | .729d |
a Indicates occlusion of the horizontal segment (M1) of the MCA at or proximal to the lenticulostriate arteries.
b χ2 test.
c Insular segment of the MCA.
d Fisher exact test.
e Unpaired t test.