Main demographic, clinical, and structural MR imaging characteristics of patients with fatigued and nonfatigued MS and HC
| HC | Nonfatigued MS | Fatigued MS | |
|---|---|---|---|
| No. of subjects | 14 | 14 | 10 |
| Women/men | 8/6 | 8/6 | 6/4 |
| Mean age (yr) | 38.7 ± 8.4 | 38.6 ± 8.5 | 38.0 ± 7.7 |
| Mean disease duration (yr) | – | 10.6 ± 6.6 | 8.2 ± 6.2 |
| Median EDSS (range) | 1.5 (0–1.5) | 1.5 (1.5–2.0) | |
| Mean FSS (range) | – | 2.1 (1.4–3.3) | 4.4 (4–6.1) |
| Median T2 LV (mL) | – | 8.9 ± 10.7 | 7.7 ± 5.0 |
| Mean NBV (mL) | 1649 ± 48 | 1560 ± 51 | 1596 ± 79 |
| Mean WMV (mL) | 822 ± 42 | 790 ± 60 | 801 ± 55 |
| Mean GMV (mL) | 826 ± 58 | 770 ± 45 | 795 ± 66 |