Clinical outcomes
| NINDS rtPA (n = 182) | NINDS Placebo (n = 211) | IMS I Study (n = 80) | IMS II Study (n = 81) | Present Study (n = 12) | |
|---|---|---|---|---|---|
| Mortality rate at 3 months (%) | 21 | 24 | 16 | 16 | 0 |
| Symptomatic ICH (%) | 6.6 | 1 | 6.3 | 9.9 | 0 |
| Asymptomatic ICH (%) | 6.0 | 5.7 | 42.5 | 32.1 | 41 |
| mRS 0–2 at 3 months (%) | 39 | 28 | 43 | 46 | 75 |
Note:—NINDS indicates National Institute of Neurological Disorders and Stroke; IMS, Interventional Management of Stroke; ICH, intracerebral hemorrhage.