Table 2:

ROI and tract-based mean ADC and mean FA values of NAWM

	Controls	Patients	P Value
Region 1: genu of CC
ROI mean ADC	0.77 ± 0.03	0.91 ± 0.14	.002^a
ROI mean FA	0.80 ± 0.09	0.73 ± 0.10	.28
Tract mean ADC	0.78 ± 0.03	0.87 ± 0.10	.041^a
Tract mean FA	0.62 ± 0.04	0.57 ± 0.06	.16
Region 2: Splenium of CC
ROI mean ADC	0.74 ± 0.04	0.88 ± 0.11	.0039^a
ROI mean FA	0.86 ± 0.05	0.78 ± 0.05	.0059^a
Tract mean ADC	0.79 ± 0.05	0.85 ± 0.07	.049^a
Tract mean FA	0.72 ± 0.03	0.66 ± 0.04	.002^a
Region 3: PLIC
ROI mean ADC	0.69 ± 0.03	0.72 ± 0.02	.0098^a
ROI mean FA	0.69 ± 0.05	0.66 ± 0.03	.25
Tract mean ADC	0.71 ± 0.03	0.75 ± 0.04	.0098^a
Tract mean FA	0.61 ± 0.03	0.57 ± 0.03	.0098^a
Region 4: CP
ROI mean ADC	0.71 ± 0.03	0.78 ± 0.05	.037^a
ROI mean FA	0.73 ± 0.05	0.69 ± 0.04	.19
Tract mean ADC	0.72 ± 0.02	0.78 ± 0.04	.0098^a
Tract mean FA	0.63 ± 0.03	0.60 ± 0.03	.016^a
Region 5: Anatomic region for SLF
ROI mean ADC	0.71 ± 0.03	0.74 ± 0.04	.014^a
ROI mean FA	0.60 ± 0.06	0.47 ± 0.07	.0039^a
Tract mean ADC	0.72 ± 0.03	0.79 ± 0.07	.0039^a
Tract mean FA	0.54 ± .04	0.45 ± 0.05	.0098^a
Region 6: Anatomic region for IFOF and UF
ROI mean ADC	0.76 ± 0.03	0.82 ± 0.03	.002^a
ROI mean FA	0.53 ± 0.04	0.45 ± 0.07	.018^a
Tract mean ADC	0.78 ± 0.03	0.85 ± 0.05	.002^a
Tract mean FA	0.51 ± 0.03	0.44 ± 0.06	.014^a
All NAWM
ROI mean ADC	0.73 ± 0.02	0.79 ± 0.04	.0020^a
ROI mean FA	0.68 ± 0.02	0.61 ± 0.04	.0098^a
Tract mean ADC	0.75 ± 0.03	0.81 ± 0.05	.0098^a
Tract mean FA	0.61 ± 0.03	0.55 ± 0.03	.002^a

Note:—SLF indicates superior longitudinal fascicle; IFOF, inferior fronto-occipital fascicle; UF, uncinate fascicle; NAWM, normal-appearing white matter; ADC, apparent diffusion co-efficient, ×10⁻³ mm²/s.
a Statistically significant.