Mean normalized volumes and MT ratios of the cerebral cortical GM in 15 healthy controls and 15 HD carriers
| Lobes | Mean Normalized Volume (mm3) | Mean MT Ratio | ||||
|---|---|---|---|---|---|---|
| Controls | HD Carriers | P Valuea | Controls | HD Carriers | P Valuea | |
| Frontal | 202 ± 16 | 179 ± 19 | <.01 | 55.1 ± 0.9 | 50.7 ± 3.5 | <.001 |
| Parietal | 161 ± 15 | 135 ± 20 | <.01 | 54.5 ± 0.8 | 51.4 ± 2.9 | <.01 |
| Temporal | 143 ± 11 | 128 ± 13 | .02 | 54.9 ± 0.8 | 51.7 ± 2.7 | <.01 |
| Occipital | 91 ± 10 | 72 ± 10 | <.01 | 53.2 ± 1.3 | 48.2 ± 3.4 | <.01 |
a Mann-Whitney U test with Bonferroni correction.