Vessel | Animal 7 Renal A | Animal 8 Renal A | Animal 9 Renal A | |||||
---|---|---|---|---|---|---|---|---|
Lower L | Upper L | Upper R | Lower R | Lower L | Upper L | Upper R | Lower R | |
Vessel diameter | 1.8 | 2 | 2 | 1.8 | 1.8 | 2.3 | 2.0 | 2.0 |
Chronic period (days) | 33 | 33 | 33 | 33 | 102 | 102 | 91 | 91 |
TIMI post-chronic period | 3 | 3 | 3 | 3 | 2 | 3 | 3 | 3 |
Distal embolizationa | No | No | No | No | No | No | No | No |
Vessel damagea | No | No | No | No | Nob | Nob | No | No |
Vasospasma | Present only at time 0 | Present only at time 0 | Present only at time 0 | Present only at time 0 | Present only at time 0 | Present only at time 0 | Present only at time 0 | Present only at time 0 |
Thrombusa | No | No | No | No | No | No | No | No |
Proliferation, medial/adventitialc | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thickening, intimalc | 2 | 2 | 2 | 2 | 1 | 2 | 2 | 2 |
Inflammation, chronicc | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inflammation, granulomatousc | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stenosis | 5% | 5% | 1% | 5% | 1% | 5% | 5% | 5% |
a Distal embolization, vessel damage, vasospasm, and thrombus were evaluated at time 0 and at the chronic period. The rating is for both time periods, unless stated otherwise.
b There were no angiographic observations of vessel damage, but the entire kidney was diminished in size.
c Severity grade of lesions at histology: 1 = minimal, 2 = mild, 3 = moderate, 4 = marked.