Table 1:

Mean (± SD) global and regional CC measures for patients with NF-1 and matched controlsa

Patients with NF-1 (n= 10)Matched Controls (n= 10)t Statistic (df = 9)
Global CC measures
    Central length (mm)94.1 (5.7)85.4 (5.7)3.46b
    Area (mm2)708.4 (74.9)587.2 (53.8)4.15b
    Total brain volume (cm3)1050 (110)1010 (90)0.89
Factor groupings (mm)
    F1 (widths 3–18)13.0 (3.2)14.5 (1.6)1.33
    F2 (widths 22–39)9.2 (1.7)7.3 (0.7)3.21b
    F3 (widths 49–62)7.9 (1.4)6.6 (0.7)2.58c
    F4 (widths 65–74)7.9 (0.8)6.2 (0.7)5.09b
    F5 (widths 77–85)12.7 (1.9)10.8 (1.2)2.67c
    F6 (widths 89–94)14.3 (1.7)13.2 (1.9)1.40
    F7 (widths 95–99)5.1 (0.4)4.6 (0.3)2.55c
  • a There is no significant difference between the total brain volumes of the subjects with NF-1 and controls, but the area and length of the CC are larger in NF-1. The factor groupings are also presented pictorially in Fig 1.

  • b P <.05 after the Bonferroni correction.

  • c P < .05 before the Bonferroni correction (.05/10) only.