Clinical outcomes, secondary end points, and HT in patients undergoing Merci thrombectomy for acute ischemic strokea
| Age <80 yr (n = 75) | Age ≥80 yr (n = 31) | Pb | Age 65–79 yr (n = 33) | Pb | |
|---|---|---|---|---|---|
| Admission NIHSS | 18 (13–22) | 20 (18–23) | .1 | 17 (15–23) | .3 |
| Hospital length of stay (days)c | 10.4 ± 8.0 | 8.3 ± 5.0 | .3 | 6.2 ± 3.0 | .1 |
| Stroke-related death | 11 (15) | 15 (48) | 5.5 (2.1–14.1) | 8 (24) | 2.9 (1.0–8.5) |
| Discharge NIHSS | 6.5 (2–42) | 42 (6–42) | .006 | 11 (3–42) | .09 |
| Discharge NIHSS in survivorsd | 5 (2–12) | 5.5 (2–11) | 1 | 4 (0–11) | .8 |
| NIHSS change | 4.2 ± 14.4 | −4.9 ± 16.9 | .01 | 1.7 ± 15.8 | .1 |
| NIHSS change in survivorsd | 9.4 ± 8.6 | 10.4 ± 5.5 | .7 | 10.1 ± 7.5 | .9 |
| Discharge mRS | 4 (1–5) | 5 (3.5–6) | .006 | 3 (0.5–4) | .1 |
| Discharge mRS in survivorsd | 3 (1–4) | 3.5 (2–4) | .9 | 2 (0–4) | .7 |
| mRS ≤2 in survivorsd | 25/62 (40) | 6/16 (38) | .9 (.3–2.8) | 11/23 (48) | 0.7 (.2–2.4) |
| HTe | |||||
| Any HT within 72 hr | 30/72 (42) | 17/28 (61) | 2.2 (.9–5.3) | 13/30 (43) | 2.0 (.7–5.8) |
| Symptomatic HT within 72 hr | 7/72 (10) | 3/28 (11) | .9 (.2–3.7) | 2/30 (7) | 1.7 (.3–10.9) |
| Parenchymal HT within 72 hr | 9/72 (13) | 4/28 (14) | 1.2 (.3–4.1) | 3/30 (10) | 1.5 (.3–7.4) |
a Clinical measure, No. (%) unless otherwise specified; all NIHSS and mRS values except NIHSS change are shown as median (interquartile range).
b ORs (95% CI) are shown for selected comparisons.
c One patient with a prolonged hospitalization due to surgery unrelated to the stroke was excluded from LOS analysis.
d Patients who died were not analyzed in these comparisons.
e Three patients in each group did not undergo imaging by 72 hours to determine HT.