Relationship between in vivo 3T carotid plaque components and recent ipsilateral thromboembolic symptoms for 40 patients with severe carotid stenosis measured by contrast-enhanced MR angiography
| Variable | Symptomatic (n = 7) | Asymptomatic (n = 33) | OR (95% CI) | PValue | AUC |
|---|---|---|---|---|---|
| Plaque burden | |||||
| % wall volume | 63.7 ± 7.6 | 60.7 ± 8.8 | 1.52 (0.58–4.02)a | .395 | 0.602 |
| % stenosis on MRA | 86.3 ± 6.5 | 81.7 ± 6.9 | 2.72 (0.77–9.65)a | .121 | 0.669 |
| Ulceration on MRA | 86% | 36% | 10.50 (1.13–97.91) | .039 | 0.747 |
| Prevalence of plaque components | |||||
| Fibrous cap thin/ruptured | 57% | 52% | 1.26 (0.24–6.50) | .787 | 0.528 |
| Lipid-rich necrotic core | 57% | 64% | 0.76 (0.15–3.99) | .748 | 0.481 |
| Hemorrhage | 43% | 36% | 1.31 (0.25–6.88) | .748 | 0.532 |
| Calcifications | 86% | 73% | 2.25 (0.24–21.38) | .480 | 0.565 |
| Volume of plaque components | |||||
| Lipid-rich necrotic core | 9.7 ± 11.8 | 10.6 ± 13.4 | 0.94 (0.49–1.82)a | .863 | 0.481 |
| Hemorrhage | 2.8 ± 3.7 | 4.1 ± 7.4 | 0.73 (0.18–2.96)a | 0.661 | 0.519 |
| Calcifications | 6.6 ± 5.5 | 5.0 ± 6.1 | 1.51 (0.43–5.31)a | 0.525 | 0.608 |
a ORs for a 10% increase.