TABLE 2:

Patients perineural tumor spread along the auriculotemporal nerve, as determined with imaging findings

Patient No.DiagnosisCranial Nerve PalsySymptomsInvolvementAdditional Imaging Findings
Facial Nerve Main TrunkAuriculotemporal NerveCranial Nerve VSkull BaseIntracranial
1Poorly differentiated adenocarcinomaVII palsy at presentationFacial weaknessYesYesYesTemporal bone along the facial canalNoNone
2Squamous cell carcinomaVII palsy at presentation, V3 3 mo laterPretragal massYesYesYesNoYes, 7 m after initial diagnosisNone
3Poorly differentiated squamous cell carcinomaClinically suspected auriculotemporal nerve dysfunction, V3 palsy 10 mo laterEar discomfort, TMJ tendernessYesYesYesAt the foramen spinosum and ovaleNoSpread along the middle meningeal artery
4Poorly differentiated adenocarcinomaVII and V palsy, clinically suspected auriculotemporal nerve dysfunctionRetromandibular and pretragal painYesYesYesAt the right foramen ovaleYes, 14 mo after initial diagnosisInvolvement of infratemporal fossa
5NeurofibromaV3 palsy at presentationPain and mass in the right mandibular regionNoYesYesNoNoNone
6Moderately differentiated squamous cell carcinomaBilateral V, right VI, and IX palsyEar pain, TMJ dysfunctionNoYesYesYesYesInvolvement of infratemporal fossa
7Squamous cell carcinomaVII palsy for 22 moParotid pain and swelling, preauricular painYesYesNoNoYesInvolvement of V1