TABLE 1:

Specificity in the unblinded evaluation

Dose Group and Postdose Time PointTotal Lymph NodesSequence Specificity (%)
T2-WeightedFFE-25FFE-80
1.1 mg Fe/kg
 6 h41781220
 12 h419056*74*
 24 h418062*87*
 36 h415662*65
1.7 mg Fe/kg
 6 h25883244
 12 h25926484
 24 h251007284
 36 h25928476
2.6 mg Fe/kg
 6 h25925668
 12 h25968496
 24 h2510096100
 36 h251009692
3.4 mg Fe/kg
 6 h19956389
 12 h191008395
 24 h19898495
 36 h19797979
  • Note.—The specificity was based on the signal intensity and lymph node architecture. A decrease in the signal intensity of a heterogeneous lymph node indicated a false-positive result.

  • * The total number of lymph nodes was 39.

  • The total number of lymph nodes was 40.

  • The total number of lymph nodes was 18.