Mean metabolite concentrations (mM, mean ± SD)
| Occipital WM | Centrum Semiovale | Occipital GM | Insular GM | ||
|---|---|---|---|---|---|
| Patient 1 (episode) | Cho | 2.6 ± 0.8 | 2.8 ± 0.8 | 2.2 ± 0.6 | 2.9 ± 1.1 |
| Cr | 8.4 ± 2.2 | 7.4 ± 2.0 | 7.1 ± 1.2 | 7.6 ± 2.3 | |
| NAA | 6.9 ± 1.9 | 6.8 ± 1.7 | 5.2 ± 1.3 | 6.0 ± 3.0 | |
| Patient 2 (episode) | Cho | 3.3 ± 0.4* | 3.7 ± 0.3* | 2.7 ± 0.6* | 3.2 ± 0.5* |
| Cr | 6.8 ± 1.8 | 8.2 ± 1.6* | 7.9 ± 1.5* | 7.9 ± 1.2* | |
| NAA | 6.3 ± 0.8* | 7.1 ± 0.7* | 6.0 ± 1.5 | 6.1 ± 0.6 | |
| Patient 2 (follow-up) | Cho | 2.1 ± 0.3 | 2.3 ± 0.3 | 1.6 ± 0.4 | 1.7 ± 0.5 |
| Cr | 6.6 ± 1.4 | 6.9 ± 1.2 | 6.4 ± 1.4 | 6.3 ± 1.2 | |
| NAA | 7.9 ± 0.7 | 7.9 ± 0.3 | 6.8 ± 1.1 | 6.2 ± 0.8 |
Note.—WM indicates white matter; GM, gray matter; Cho, choline; Cr, creatine; NAA, N-acetylaspartate.
* P < .05 for comparison of values during episode and at follow-up (Mann-Whitney Nonparametric Test).