Average diffusivity (SD) metrics in gray matter of control volunteers and of different multiple sclerosis phenotypes studied
| Controls | All MS | RRMS | SPMS | PPMS | |
|---|---|---|---|---|---|
| Average D̅ | 1.02 (0.04) | 1.13 (0.09) | 1.05 (0.05) | 1.20 (0.07) | 1.13 (0.06) |
| D̅ peak height | 73.0 (11.5) | 55.0 (12.7) | 67.0 (11.2) | 45.8 (7.6) | 52.3 (8.1) |
| D̅ peak location | 0.86 (0.04) | 0.92 (0.08) | 0.89 (0.06) | 0.95 (0.09) | 0.90 (0.07) |
Note.—Average diffusivity and the peak location of the average diffusivity histogram are expressed in units of mm2s−1 × 10−3. RRMS indicates relapsing-remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis; PPMS, primary progressive multiple sclerosis; D̅ = mean diffusivity. For further details and statistical analysis, see text.