TABLE 3:

Results of the age-adjusted, brain volume-adjusted, and Bonferroni-corrected comparisons among control volunteers and different multiple sclerosis clinical phenotypes

	Average D̅	D̅ Histogram Peak Height	D̅ Histogram Peak Position
Control volunteers vs. all patients with MS	<0.00001	<0.00001	0.003
Control volunteers vs. RRMS	0.93	0.08	0.98
Control volunteers vs. PPMS	0.00001	0.00001	0.14
RRMS vs. SPMS	<0.00001	<0.00001	0.0009
PPMS vs. SPMS	0.0002	0.07	0.12

Note.—MS indicates multiple sclerosis; RRMS, relapsing-remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis; PPMS, primary progressive multiple sclerosis. For further details and statistical analysis, see text.