Comparisons of Gray Matter Magnetization Transfer Ratio and Volume Measurements in Different Age and Sex Groups
| Measurements | Mean ± SD | P Values | Mean ± SD | P Value | ||
|---|---|---|---|---|---|---|
| Age < 50 y | Age ≥ 50 y | Female Subjects | Male Subjects | |||
| Mean (%) | 30.2 ± 0.5 | 29.3 ± 0.9 | <.0001 | 29.9 ± 0.7 | 29.8 ± 0.9 | .672 |
| Median (%) | 31.8 ± 0.6 | 31.2 ± 0.9 | .006 | 31.6 ± 0.7 | 31.4 ± 0.9 | .221 |
| First Quartile (%) | 28.3 ± 0.7 | 26.9 ± 1.4 | <.0001 | 27.8 ± 1.2 | 27.6 ± 1.3 | .579 |
| Third Quartile (%) | 34.3 ± 0.7 | 34.3 ± 0.7 | .988 | 34.4 ± 0.7 | 34.2 ± 0.7 | .444 |
| Peak Loc (%) | 32.5 ± 0.7 | 32.9 ± 0.9 | .07 | 32.9 ± 0.8 | 35.0 ± 0.8 | .31 |
| Peak HT (×10−3) | 98.5 ± 10.3 | 86.3 ± 12.4 | .0003 | 94.6 ± 13.6 | 92.1 ± 11.2 | .487 |
| Volume (mL) | 708.5 ± 96.7 | 627.0 ± 85.5 | .002 | 642.4 ± 89.0 | 724.5 ± 97.0 | .004 |
Note.—Peak Loc indicates location and Peak HT, normalized peak height of magnetization transfer ratio histogram.