Comparisons of White Matter Magnetization Transfer Ratio and Volume Measurements in Different Age and Sex Groups
| Measurements | Mean ± SD | P Values | Mean ± SD | P Value | ||
|---|---|---|---|---|---|---|
| Age < 50 y | Age ≥50 y | Female Subjects | Male Subjects | |||
| Mean (%) | 33.5 ± 0.7 | 32.6 ± 1.0 | .0003 | 33.1 ± 0.9 | 33.1 ± 1.1 | .964 |
| Median (%) | 34.7 ± 0.8 | 34.0 ± 0.9 | .0058 | 34.5 ± 0.8 | 34.2 ± 1.0 | .153 |
| First Quartile (%) | 32.5 ± 0.8 | 31.4 ± 1.2 | .0002 | 32.1 ± 1.1 | 31.9 ± 1.2 | .638 |
| Third Quartile (%) | 36.4 ± 0.7 | 36.1 ± 1.0 | .209 | 36.3 ± 0.8 | 36.2 ± 0.8 | .803 |
| Peak Loc (%) | 35.0 ± 0.7 | 34.8 ± 0.9 | .35 | 35.0 ± 0.8 | 34.8 ± 0.6 | .31 |
| Peak HT (×10−3) | 146.6 ± 17.3 | 129.8 ± 16.8 | .001 | 141.8 ± 18.7 | 136.9 ± 19.3 | .356 |
| Volume (mL) | 504.2 ± 72.3 | 447.4 ± 52.3 | .002 | 475.9 ± 72.5 | 489.3 ± 67.8 | .50 |
Note.—Peak Loc indicates peak location and Peak HT, normalized peak height of magnetization transfer ratio histogram.