Summary of imaging findings associated with neonatal alloimmune thrombocytopenia
| Case No. | Imaging Modality and Age | Imaging Findings | Clinical Outcome |
|---|---|---|---|
| 1 | US, 1 mo | Large left temporal and right frontotemporal porencephalic cysts | Seizures, cerebral palsy, left hemiplegia, developmental delay, microcephaly |
| CT, 1–6 yr | Bilateral porencephalic cysts, right lateral ventricular enlargement | ||
| MR imaging, 8 yr | Multilocular left temporal porencephalic cyst, right frontotemporal porencephaly with ventricular communication (after fenestration surgery), right lateral ventricular enlargement | ||
| 2 | US, days 1 and 3 | Bilateral choroid plexus hemorrhages, thick echogenic extraaxial spaces, left temporal porencephalic cyst with ventricular communication, ventriculomegaly | Seizures, developmental delay |
| CT, day 4 | Choroid plexus hemorrhages, acute on chronic bilateral extraaxial hemorrhages, left temporal porencephaly | ||
| MR imaging, day 8 | Choroid plexus hemorrhages (hemosiderin), hemosiderin over cerebellar sulci, mixed signal loculated extraaxial collections, left temporal porencephalic cyst with ventricular communication, lateral ventriculomegaly with colpocephaly | ||
| 3 | US, day 2 | Large right temporal porencephalic cyst with clot, right occipital lobe porencephalic cyst with clot communicating with lateral ventricle | Seizures, developmental delay, microcephaly |
| CT, day 3 | Right-sided porencephalic cysts with clot, small acute parenchymal hemorrhage in right frontal white matter, dilated right lateral ventricle | ||
| 4 | US, day 3 | Large left frontotemporal porencephalic cyst with clot communicating with lateral ventricle, large right parietotemporal and occipital porencephalic cyst with clot and ventricular communication, ventriculomegaly (colpocephaly) | Died during neonatal period |
| CT, day 3 | Bilateral large porencephalic cysts with clot and ventricular communication, ventriculomegaly | ||
| 5 | CT, 4 mo | Large right occipitotemporal porencephalic cyst communicating with right lateral ventricle, mild right lateral ventricular dilatation | Seizures, blindness, developmental delay |
| MR imaging, 2 yr | Large right temporal porencephalic cyst with ventricular communication, ventriculoperitoneal shunt, reduced periventricular/periatrial white matter with increased fluid-attenuated inversion recovery/T2 signal (gliosis) | ||
| 6 | Fetal MR imaging, 21/40 | Left extraaxial hemorrhage with mass effect, signal change left parietal lobe with cortical breech, porencephaly? | Microcephaly, seizures |
| Resolving extraaxial hemorrhage, extensive parietotemporal porencephaly with hemosiderin lining cyst, ex vacuo dilation right lateral ventricle, high signal right temporal lobe, delayed maturation with delayed sulcation | |||
| MR imaging, 5 mo | Left parietotemporal porencephaly, ventriculomegaly, neuronal migrational disorder with extensive polymicrogyria and periventricular heterotopia with almost double cortex appearance, abnormal signal right temporal and parietal white matter |