Note.—A, ADC value obtained with small region of interest (ROI) size (22 ± 5 mm²) with observer 1 on the right hemisphere; B, ADC value obtained with small ROI size (22 ± 5 mm²) with observer 2 on the right hemisphere; C, ADC value obtained with larger ROI size (62 ± 6 mm²) with observer 1 on the right hemisphere; D, ADC value obtained with larger ROI size (62 ± 6 mm²) with observer 2 on the right hemisphere; E, ADC value obtained with small ROI size (22 ± 5 mm²) with observer 1 on the left hemisphere; F, ADC value obtained with small ROI size (22 ± 5 mm²) with observer 2 on the left hemisphere; G, ADC value obtained with larger ROI size (62 ± 6 mm²) with observer 1 on the left hemisphere; H, ADC value obtained with larger ROI size (62 ± 6 mm²) with observer 2 on the left hemisphere.