Table 3:

Clusters in which HIV+ children had significantly greater MD compared with controlsa

Cluster LocationSize (mm3)CoordinatesADRD
ControlHIV+P ValueControlHIV+P Value
ILF/SLF
    Right temporal750332, 0, −241.19 (0.03)1.23 (0.03).0010.62 (0.02)0.65 (0.03)<.001
    Left putamen6916−29, −26, −21.20 (0.03)1.25 (0.03).0010.59 (0.02)0.62 (0.03)<.001
CST
    Right brain stem91621, −15, −91.25 (0.04)1.29 (0.03).010.58 (0.02)0.63 (0.02)<.001
IFOF
    Left temporal555−37, −10, −171.19 (0.05)1.25 (0.04).0030.66 (0.02)0.70 (0.04)<.001
Forceps minor
    Left frontal336−19, 43, 141.20 (0.06)1.24 (0.06).040.63 (0.03)0.67 (0.05).0030
    Left frontal266−17, 42, −11.22 (0.06)1.26 (0.06).050.62 (0.03)0.65 (0.05).0040
UF
    Right frontal33015, 38, −121.19 (0.05)1.25 (0.06).0030.64 (0.03)0.67 (0.04).0046
  • Note:—ILF/SLF indicates inferior/superior longitudinal fasciculus; IFOF, inferior fronto-occipital fasciculus; UF, uncinate fasciculus.

  • a Values are mean (SD).