Patient No./Age (y)/Sex | Signs and Symptoms | Imaging Findings | White Blood Cell Count (WBC) | CSF Analysis | |
---|---|---|---|---|---|
Protein (mg/L) | Brucella* (SAT, 2ME) | ||||
1/26/M | Headache, ↓hearing, psychosis | MR brain: normal. | 4 | 603 | 320, 160 |
2/51/M | Confusion, spastic gait, ↓hearing | MR: periventricular white matter hyperintense lesion (T2 + FLAIR). | 6 | 692 | 160, 80 |
3/30/F | Headache, deafness, papilledema, sensory ataxia, areflexia | MR brain: enhancing granuloma suprasellar region (T1 + contrast). | 373 | 8000 | 1280, 640 |
4/59/M | Fever, ↓hearing, ataxia, lower limb weakness, areflexia, Babinski | CT brain: normal. MR brain: periventricular white matter hyperintense lesions (T2 + FLAIR). | 70 | 1900 | 320, 320 |
5/25/M | Deafness | MR brain: normal. | 1 | 521 | 40, 40 |
6/36/M | ↓Hearing, ataxia, nystagmus | CT brain: normal. MR brain: basal meningeal enhancement (T1 + contrast). | 219 | 8300 | 640, 640 |
7/32/M | ↓Hearing, spasticity, bilateral Babinski | MR brain: right frontal subcortical high signal intensity (T2). | 6 | 1093 | 640, 640 |
8/29/F | Deafness | MR brain: normal. | 82 | 1900 | 640, 320 |
9/32/M | ↓Hearing, lower limb weakness, areflexia | MR lumbar spine: enhancement of nerve root (T1 + contrast). | 270 | 6637 | 1280, 640 |
10/58/M | Fever, ↓hearing, ataxia | CT brain: normal. | 490 | 7930 | 1280, 1280 |
11/17/M | Fever, lower limb weakness, areflexia | MR lumbar spine: enhancement of nerve root (T1 + contrast). | 65 | 2308 | 160, 160 |
12/28/F | ↓Hearing | CT brain: normal. | 20 | 747 | 80, 80 |
13/50/M | Confusion, seizures, behaviour change, ↓hearing | CT brain: bihemisphere white matter hypoattenuation, left caudate lacunae, subthalamic hematoma. MR: diffuse white matter hyperintense lesions (T2 + FLAIR), caudate lacunae, increased signal intensity in pons and left cerebral peduncle (T2). | 900 | 7536 | 180, 80 |
14/70/M | ↓Hearing, spastic paraparesis, ataxic gait | MR brain: diffuse white matter hyperintense lesions (T2 + FLAIR) and basal meningeal enhancement (T1 + contrast). MR spine: normal. | 17 | 2641 | 160, 160 |
15/30/F | Headache, sixth nerve palsy, papilledema, ↓hearing | MR and CT: normal. | 500 | 2370 | 640, 640 |
16/30/M | Headache, sixth nerve palsy, papilledema, ↓hearing, neck stiffness | MR: normal. | 42 | 880 | 40, 20 |
17/29/M | ↓Hearing, spastic paraparesis | MR brain: normal. MR spine: atrophy. | 1 | 460 | 320, 160 |
18/32/F | ↓Hearing | MR: normal. | 6 | 1599 | 320, 320 |
19/25/F | ↓Hearing, headache | MR: normal. | 15 | 2153 | 80, 80 |
20/63/M | Recurrent transient ischemic attacks, confusion, ↓hearing | CT: periventricular hypoattenuations, enhancement of tentorium. MR: periventricular white matter hyperintense lesions (T2 + FLAIR), right cerebellum and pons increased signal intensity (T2). | 150 | 1000 | 80, 80 |
21/65/F | Headache, confusion, neck stiffness | MR: diffuse white matter hyperintense lesions (T2 + FLAIR), left caudate lacunae. | 272 | 2000 | 640, 640 |
22/20/F | Lower limb weakness, areflexia | MR spine: lumbar nerve root enhancement (T1 + contrast). | 32 | 1797 | 1280, 640 |
23/47/F | ↓Hearing, lower limb weakness, areflexia | MR spine: normal. | Not performed |
Note.—↓ indicates decreased; T2, T2-weighted images; T1 + contrast, gadolinium-enhanced T1-weighted images.
* By standard agglutination test before and after precipitation by 2-mercapto-ethanol.