TABLE 2:

ADC values in three patients with PBD and age-matched controls

ADC values × 10−3 mm2/sN12 Months16 Months80 Months
PatientControlDiff.%PatientControlDiff.%PatientControlDiff.%
Mean (SD)Mean (SD)Mean (SD)Mean (SD)Mean (SD)Mean (SD)
Genu of corpus callosum12111 (7)107 (9)4498 (8)75 (9)223092 (10)69 (5)2435
Splenium of corpus callosum12115 (12)122 (23)−7−698 (9)83 (7)1518110 (10)88 (16)2225
Parietal corona radiataR51131 (7)106 (8)2524117 (5)102 (8)1515102 (7)93 (15)89
L51137 (5)108 (6)3028129 (7)109 (4)201994 (8)91 (6)23*
Frontal corona radiataR51127 (4)105 (6)2322115 (6)91 (5)242794 (5)73 (5)2028
L51124 (5)110 (11)1413114 (5)94 (4)212292 (5)84 (5)810
Centrum semiovaleR51131 (6)95 (3)3537106 (5)100 (5)66100 (9)84 (6)1620
L51141 (4)94 (5)4749110 (4)99 (5)111195 (5)91 (9)44
  • Note.—N indicates number of pixels per region of interest; significance determined with t test:

  • * P < .05;

  • P < .01;

  • P < .001.