TABLE 1:

Compression time, balloon diameter, and histologic and MR imaging results

AnimalCompression Time (min)Balloon Size (mm)H&E Grade*βAPP Grade*MR ImagingSCO (%)
EnhancementSTIRT1T2
1304000None29
2304020None+31
3307331None79
4307230None62
5307301None+67
6307300++69
7120200012.5
8120200020
91204221+38
10120400028
111204021++43
121207201+78
132404301+56
142404311+44
152407301+82
16240200017
17240200012
  • * Subjective grading system: 0 indicates none; 1, mild; 2, moderate; and 3, severe.

  • T1 indicates T1-weighted; T2, T2-weighted; +, positive; −, negative.