Association of Acute Phase MR Imaging Parameters with Outcome of ≥20% Recovery at 3 Months: Individual Parameter Effect
| Variable | Odds Ratio (95% CI)* | P Value* | Odds Ratio (95% CI)† | P Value† |
|---|---|---|---|---|
| Tissue signature | – | – | 2.40 (0.98, 5.89) | 0.06 |
| rADC | 36.41 (4.92, 269.19) | <0.01 | 0.09 (0.002, 4.07) | 0.18 |
| rT2 | 0.06 (0.01, 0.28) | <0.01 | 0.93 (0.05, 18.35) | 0.94 |
| ADC | 1.005 (1.003, 1.007) | <0.01 | 1.001 (0.99, 1.006) | 0.86 |
| T2 | 0.99 (0.97, 1.011) | 0.29 | 0.97 (0.93, 1.02) | 0.24 |
| Stroke onset to MR imaging time | 0.97 (0.92, 1.01) | 0.13 | 0.97 (0.92, 1.12) | 0.75 |
| rt-PA treatment | 1.51 (0.61, 3.75) | 0.37 | – | – |
Note.—CI indicates confidence interval; –, invalid test; rADC, relative apparent diffusion coefficient; rT2, relative T2, ADC, apparent diffusion coefficient; rt-PA, recombinant tissue plasminogen activator.
* Testing for individual MR image parameter effect or the interaction of MR imaging parameter by rt-PA treatment effect adjusting for acute phase lesion size volume and correlation among sections and among tissues.
† Testing the rt-PA by MR imaging parameter interaction.