Perfusion and diffusion MR parameter ratios for infarct core (region 1), penumbra that infarcts (region 2), and hypoperfused tissue that recovers (region 3)

ParameterRegion 1Region 2Region 3P Value*
Perfusion
 rCBF0.32 ± 0.110.46 ± 0.130.58 ± 0.12<.001
(0.16–0.61)(0.24–0.79)(0.36–0.84)
 rCBV0.56 ± 0.210.80 ± 0.250.91 ± 0.18.056
(0.16–0.88)(0.43–1.44)(0.53–1.21)
 MTT1.70 ± 0.421.74 ± 0.421.65 ± 0.43.484
(0.93–2.70)(0.89–2.62)(0.65–2.70)
Diffusion
 ADC0.63 ± 0.120.90 ± 0.110.96 ± 0.05.018
(0.45–0.93)(0.69–1.12)(0.85–1.06)
 DWI1.84 ± 0.411.13 ± 0.081.08 ± 0.07.014
(1.07–2.71)(1.02–1.34)(0.95–1.22)
 FA1.13 ± 0.201.02 ± 0.101.02 ± 0.06.862
(0.83–1.64)(0.84–1.18)(0.92–1.10)
  • Note.—DWI indicates DW image signal intensity. Data are mean ratios ± SD.

    Numbers in parentheses are the range.

  • * P values are for the comparison between region 2 and region 3.