TABLE 3:

ADC values [× 10−6 s/mm2; b = 1000 s/mm2] in sCJD patients and controls

AreaPatientsa (mean ± SEM)Controls (mean ± SEM)Pb (unpaired two-tailed Student t test)
Caudate nucleus548 ± 27767 ± 35<0.0001
Putamen585 ± 28754 ± 22<0.0001
Mediodorsal thalamic nucleus664 ± 28800 ± 240.0011
Pulvinar:
 1. All patients695 ± 27853 ± 15<0.0001
 2. Patients with SI changes701 ± 38c
 3. Patients without SI changes684 ± 37
Hippocampus853 ± 22871 ± 210.56
  • a In patient 1 in Table 1, the first of the three consecutive measurements was considered.

  • b P < .05 is considered significant.

  • c P = .78 (not significant) comparing sCJD patients with and those without SI changes in the thalamus.