TABLE 1:

Alginate, angiographic scores, and neointima thickness

GroupAneurysm TypeEmbolic AgentNumber of AneurysmsMedian Angiographic ScoresNeointima Thickness (μm)
T0T3 weeks
ICanine lateral wallAlginate + 125I/TGF-β16
IICanine lateral wallGelfoam sponge43394 ± 90
Canine lateral wallSponge + alginate411>1000
IIIPorcine aneurysmsAlginate122.51>1000
IVCanine lateral wallAlginate422.5NA
Canine bifurcationAlginate420NA
VAlginate832238 ± 226
VICanine lateral wallAlginate block103*1*255 ± 142
Canine lateral wallAlginate block + PDGF-BB530565 ± 457
Canine lateral wallAlginate block + TGF-β1532680 ± 543
  • Note.—125 I indicates iodine-125; TGF, transforming growth factor; PDGF, platelet-derived growth factor.

  • * P = .039