TABLE 2:

Clinical characteristics of patients with asymptomatic new lesions

Age (yr)/GenderClinical DetailsDiffusion-weighted Imaging
75 M1979, left hemiparesis, dysarthria; 1992, 1998, episodes of unexplained loss of consciousness, hypertension; no symptoms for 8 months before MR imaging; MMSE score, 29Left centrum semiovale infarct
55 M1995, right hemiparesis; 1999, right hemiparesis, dysarthria; no symptoms for 7 months before MR imaging; gait apraxia, pseudobulbar palsy, MMSE score, 25Right frontal subcortical lacunar infarct
74 M1991, right hemiparesis; 1998, episode of confusion; 1999, right hemiparesis and sensory loss (120 days before MR imaging); hypertension, smoker, MMSE score, 26Left lentiform nucleus lacunar infarct
65 M2001, right hemiparesis (97 days before MR imaging), hypertension; 1991, myocardial infarction, chronic renal failure; MMSE score, 30Right lentiform nucleus lacunar infarct
53 MCADASIL; 1980s, right hemisensory disturbance, migraine; 1999, encephalopathy; no symptoms for 10 months before MR imaging; MMSE score, 30Left centrum semiovale infarct
49 MCADASIL; multiple events affecting both hands (weakness, numbness), dysarthria; no symptoms for 4 months before MR imaging; MMSE score, 28Left cerebellar hemisphere lacunar infarct
  • Note.—M indicates male; MMSE, Mini-Mental State Examination; CADASIL, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.