Mean FA of clusters with statistically significant differences between patients with ALS with T1 MTC hyperintense signal and those without it and controlsa
| Patients with ALS | Controls | ||
|---|---|---|---|
| MT Hyperintensity | No MT Hyperintensity | ||
| Entire CST | 0.403 (0.024) | 0.432 (0.022) | 0.454 (0.024) |
| CST including internal capsule | 0.373 (0.024) | 0.411 (0.021) | 0.431 (0.024) |
| Middle cerebellar peduncles | 0.435 (0.020) | 0.464 (0.019) | 0.480 (0.020) |
| Pons | 0.414 (0.014) | 0.427 (0.014) | 0.445 (0.015) |
| Entire CC | 0.580 (0.018) | 0.569 (0.018) | 0.619 (0.019) |
| Genu CC | 0.517 (0.022) | 0.499 (0.022) | 0.549 (0.023) |
| Body CC | 0.530 (0.014) | 0.524 (0.014) | 0.584 (0.015) |
| Anterior body CC | 0.532 (0.013) | 0.514 (0.013) | 0.571 (0.014) |
| Posterior body CC | 0.528 (0.015) | 0.536 (0.015) | 0.602 (0.016) |
| Splenium CC | 0.679 (0.015) | 0.665 (0.015) | 0.706 (0.015) |
| Temporal white matter | 0.268 (0.013) | 0.245 (0.012) | 0.281 (0.013) |
| Parietal white matter | 0.236 (0.016) | 0.212 (0.015) | 0.255 (0.016) |
| Frontal white matter | 0.243 (0.014) | 0.234 (0.013) | 0.259 (0.014) |
↵a All P values <.05. Numbers in parentheses are SDs.