All Subjects | MGD | SGD | P Value | |
---|---|---|---|---|
Patient characteristics | ||||
No. of patients | 71 | 28 | 43 | |
No. of glands | 120 | 77 | 43 | |
Mean age (yr) | 62 (range, 21–88) | 62.4 | 62.4 | .99 |
Female | 58 (82%) | 26 (93%) | 32 (74%) | .15 |
4D-CT characteristics | ||||
Mean size of abnormal glands (mm) | 9.6 (6.2) | 7.5 (3.3) | 11.2 (7.4) | .003 |
Median size of abnormal glands (mm) | 9 | 7 | 10 | |
Preoperatively detected lesions | ||||
1 | 33 (46%) | 6 (21%) | 27 (63%) | .003 |
≥2 | 28 (39%) | 16 (58%) | 12 (28%) | |
None | 10 (14%) | 6 (21%) | 4 (9.3) | |
Biochemical markers | ||||
Serum calcium level (mg/dL) | 10.6 (0.6) | 10.4 (0.6) | 10.7 (0.6) | .08 |
Serum parathyroid hormone level (pg/mL) | 93 (43) | 87 (41) | 97 (44) | .34 |
WIN | 989 (484) | 910 (453) | 1040 (501) | .27 |
MGD scores | ||||
Composite MGD score | 3.4 (1.6) | 4.3 (1.5) | 2.7 (1.4) | <.001 |
4D-CT MGD score | 2.1 (1.4) | 2.9 (1.1) | 1.5 (1.5) | <.001 |
4D-CT sensitivity | ||||
Detection of lesions | 82 (69%) | 43 (56%) | 39 (91%) | |
Detection of all lesions in individual patients | 47 (67%) | 8 (29%) | 39 (91%) | |
Parathyroid adenoma localization | ||||
≥1 Incorrectly localized or missed adenomas | 24 (33%) | 20 (71%) | 4 (9%) | |
All adenomas localized correctly | 47 (67%) | 8 (29%) | 39 (91%) |
↵a Values are expressed as mean (SD) except as specified.