Clinical and MRI findings of the patients with MS and the NCs after 3 years of follow-up
| NC (n = 28) | cMS (n = 35) | aMS (n = 57) | |
|---|---|---|---|
| EDSS change | n.a. | 0.8 ± 0.4 (0–3.5) | 1.0 ± 0.5(0–3.0) |
| Global Δ-GMf % | 0.2 ± 0.1 (0.1–0.5) | 0.5 ± 0.2 (0.2–1.1)* | 0.5 ± 0.2 (0.3–1.0)* |
| New T2-WM lesions | n.a | 1.8 ± 1.0 (0.1–5.4) | 1.9 ± 1.5 (0–8) |
| New CLs | n.a. | 1.5 ± 1.3 (0–8) | 1.1 ± 1.5 (0–7) |
Note:—Data are reported as mean ± standard deviation (range).
Global Δ-GMf (%) indicates percentage of GM fraction change between T0 and T3; n.a., not applicable; T2-WM lesions, white matter lesions.
↵* P < 0.001 (compared with NC).