Table 3:

Multivariate predictors of lnWMHV in 201 patients with AIS

PredictorsEstimateT ValueP Value
Model 1aF = 13.42<.0001
    Age (yr)0.036.34<.0001d
    Sex0.070.45.65
    SBP0.012.24.03d
    HTN0.120.68.50
    Extracranial carotid stenosis0.030.16.87
Model 2bF = 11.45<.0001
    Age (yr)0.036.19<.0001d
    Sex0.110.66.51
    SBP0.012.43.02d
    HTN0.140.79.43
    Extracranial carotid stenosis0.110.60.55
    Intracranial arterial stenosis−0.12−0.69.49
Model 3cF = 2.35.10
    Intracranial arterial stenosis−0.01−0.05.96
    Extracranial carotid stenosis0.422.06.04d

  • ↵a Model includes all univariate predictors with P < 0.2.

  • ↵b Model includes all univariate predictors with P < 0.2 and intracranial arterial stenosis.

  • ↵c Exploratory model of the effect of subtype of large-artery stenosis on white matter hyperintensity burden.

  • ↵d Statistically significant.