Treatments and outcomes stratified by age of presentation and by patient gender
| Age | Gender | ||||||
|---|---|---|---|---|---|---|---|
| All Subjects n = 25 | ≤2 Years Old at Presentation n = 13 | >2 Years Old at Presentation n = 12 | P Value | Males n = 14 | Females n = 11 | P Value | |
| Treatments | |||||||
| Mean age of first treatment ± SD | 4.9 ± 6.5 y | 0.5 ± 0.33 y | 9.6 ± 6.8 y | .00072 | 4.5 ± 7.5 y | 5.3 ± 5.5 y | .79 |
| Median age (range) of first treatment | 1.7 y (1 day to 25 y) | 0.33 y (1 day to 1.8 y) | 8.5 y (3–25 y) | 0.78 y (1 day to 25 y) | 3 y (4 m to 16 y) | ||
| Median treatment procedures (range) | 2 (1–5) | 3 (1–5) | 2 (1–4) | .041 | 2.5 (1–5) | 2 (1–4) | .23 |
| Endovascular treatments only | 60% | 54% | 67% | .69 | 57% | 64% | 1.0 |
| Any periprocedural complication | 60% | 85% | 33% | .015 | 57% | 64% | 1.0 |
| Any symptomatic complication | 32% | 39% | 25% | .67 | 21% | 45% | .39 |
| Outcomes at last follow-up | |||||||
| Mean follow-up duration ± SD | 3.3 ± 3.3 y | 3.1 ± 2.8 y | 2.7 ± 3.7 y | .74 | 2.3 ± 2.4 y | 4.6 ± 3.8 y | .10 |
| Median (range) follow-up duration | 2 y (1 day to 13 y) | 2 y (1 day to 8 y) | 1 y (2 days to 13 y) | 1.5 y (1 day to 8 y) | 3.5 y (0.7–13 y) | ||
| Occlusion of all targeted arteriovenous shunts | 72% | 69% | 75% | 1.0 | 64% | 82% | .41 |
| Elimination of all arteriovenous shunting | 60% | 62% | 58% | 1.0 | 57% | 64% | 1.0 |
| White matter calcifications | 25% | 38% | 13% | .34 | 42% | 0% | .055 |
| Normal neurologic examination | 48% | 7.1% | 92% | <.0001 | 36% | 64% | .24 |
| Median last mRS (range) | 1 (0–6) | 3 (0–6) | 0 (0) | .0001 | 2 (0–6) | 0 (0–3) | .43 |
| Good outcome (last mRS 0–2) | 72% | 46% | 100% | .0052 | 79% | 64% | .66 |