Table 2:

Treatments and outcomes stratified by fistula complexity

All Subjects n = 25Single-Hole Fistulas n = 9Multi-Hole Fistulas n = 16P Value
Treatments
    Mean age of first treatment ± SD4.9 ± 6.5 y9.4 ± 7.3 y2.3 ± 4.5 y.021
    Median age (range) of first treatment1.7 y (1 day to 25 y)7 y (3–25 y)0.62 y (1 day to 16 y)
    Median treatment procedures (range)2 (1–5)2 (1–2)3 (1–5).003
    Endovascular treatments only60%67%56%.69
    Any periprocedural complication60%22%81%.009
    Any symptomatic complication32%22%38%.66
Outcomes at last follow-up
    Mean follow-up duration ± SD3.3 ± 3.3 y4.3 ± 4.1 y2.7 ± 2.6 y.33
    Median (range) follow-up duration2 y (1 day to 13 y)4 y (2 days to 13 y)1.8 y (1 day to 7 y)
    Occlusion of all targeted arteriovenous shunts72%78%69%1.0
    Elimination of all arteriovenous shunting60%78%38%.097
    White matter calcifications25%0%35%.26
    Normal neurologic examination48%100%19%.0001
    Median last mRS (range)1 (0–6)0 (0)2 (0–6)<.0001
    Good outcome (last mRS 0–2)72%100%56%.027