Table 1:

Parameter values (millisecond, mean ± SD) for room air-breathing (normoxia) and O₂ ventilation (hyperoxia) for both the young and the elderly groups^{^a}

Raw Parameter Values	Normoxia			Hyperoxia
Raw Parameter Values	Young	Elderly	P Value, Young∼Old	Young	Elderly	P Value, Young∼Old
T2′ Cortex	142.5 ± 9.2	124.5 ± 11.6	P < .001^b	138.7 ± 12.2	121.7 ± 9.8	P < .001^b
T2′ GM frontoparietal	126.9 ± 8.4	101 ± 11.3	P < .001^b	124.9 ± 11.4	103.2 ± 8.6	P < .001^b
T2′ Thal	116 ± 13.4	111.6 ± 12.4	P = .423	116.5 ± 9.7	111.4 ± 13.1	P = .477
T2′ WM	116.3 ± 5.7	103.8 ± 9.4	P < .001^b	117.7 ± 5.8	104.9 ± 5.9	P < .001^b
T2* Cortex	63.2 ± 2.5	60.8 ± 3.7	P = .074	62 ± 2.4	60.1 ± 2.8	P = .07
T2* GM frontoparietal	59.1 ± 1.7	57.1 ± 2.8	P = .037^b	58.7 ± 2.2	57.4 ± 2.4	P = .158
T2* Thal	50.2 ± 2.5	51.4 ± 3.9	P = .403	50.3 ± 2.1	51.6 ± 4.6	P = .255
T2* WM	51.5 ± 1.2	51.1 ± 2.5	P = .683	51.8 ± 0.9	51.2 ± 2.1	P = .182
T2 Cortex	121.5 ± 7.8	130.6 ± 13.5	P = .063	120.7 ± 6.9	134.7 ± 14.1	P = .002^b
T2 GM frontoparietal	106.6 ± 6.8	113.9 ± 13.4	P = .063	105.9 ± 8.4	123.5 ± 15.5	P = .001^b
T2 Thal	91.8 ± 2.3	100.3 ± 9.5	P < .001^b	92 ± 2.5	98.4 ± 7.2	P = .005^b
T2 WM	93.4 ± 1.7	101 ± 5.1	P < .001^b	93.7 ± 2	102.6 ± 4.9	P < .001^b
PASL	61.5 ± 9.9	43.4 ± 12.1	P < .001^b	56.2 ± 8.5	41.9 ± 12.6	P = .001^b

Note:—Thal indicates thalamus; Cortex, frontoparietal paramedian.
↵a “Cortex” is defined as the manual ROI, “GM frontoparietal” as the automated ROI, “WM” as the automated whole supratentorial white matter, and “Thal” as the manual thalamic ROI (Fig 1).
b Significant.