Table 4:

Regions of decreased qCBF in cognitively impaired patients with SPMS (PLS Analysis)

Cluster No.Brain RegionPeak Voxel CoordinatesaCluster SizeBootstrap Ratio
1Bilateral thalami (pulvinar)4, −28, 43037.20b
2Bilateral medial frontal gyrus (BA 9)0, 50, 22746.92b
3Right cingulate gyrus (BA 31)18, −38, 42426.50b
4Right caudate body10, 10, 61636.28b
5Left caudate body−12, −2, 14625.91b
6Right caudate tail20, −18, 18235.90b
  • a MNI space.

  • b P < .0001 (lower limit of significance).