Table 3:

Regions of decreased qCBV in cognitively impaired patients with SPMS (PLS Analysis)

Cluster No.Brain RegionPeak Voxel CoordinatesaCluster SizeBootstrap Ratio
1Bilateral thalami (pulvinar)0, −28, 41719.29b
2Left caudate body−12, 6, 162359.20b
3Bilateral superior frontal gyri (BA 9)−2, 52, 24649.02b
4Bilateral superior frontal gyri (BA 6)0, 22, 461617.29b
5Right caudate body12, 10, 81057.71b
6Right corpus callosum26, −46, 18267.04b
7Left caudate tail−20, −42, 81116.63b
8Right thalamus (pulvinar)20, −36, 10206.08b
  • a MNI space.

  • b P < .0001 (lower limit of significance).