Table 1:

P values comparing MD and FA in each region in 8 patients with ALD versus control subjects at times T0–T4

RegionT0 (Pre-HSCT)T1 (30–60 Days)T2 (90–120 Days)T3 (∼180 Days)T4 (∼1 Yr)
MDFAMDFAMDFAMDFAMDFA
ATWM.610.041a.119.051.162.345.269.088.071.133
BIC.278.107.103.291.955.087.831.166.372.013a
BoCC.056.256.103.076.073.227.055.247.260.154
CST-pons.863.140.370.041a.785.074.782.166.909.080
CWM.010a.020a.024a.015a.001a.024a.055.032a.013a.013a
DSCP.044a.104.213.875.117.629.916.448.6811.000
GeCC.863.246.451.291.783.1651.000.245.727.342
LL.863.105.370.350.955.165.916.201.727.173
LGN.1752 × 10−5a.5182 × 10−5a.2773 × 10−4a.08510−4a.1153 × 10−4a
MeyLo.163.002a.213.007a.084.003a.058.006a.030a.002a
MGN.044a.011a.154.016a.162.117.042a.186.030a.090
ML.177.107.614.319.695.165.274.166.727.232
NAFWM.243.107.034a.017a.133.029a.274.014a.192.082
OR.044a.010a.086.002a.084.010a.055.010a.027a.006a
OT.493.133.704.131.319.596.530.808.345.232
PLIC.351.041a.103.204.043a.165.066.186.909.082
POWM.048a.002a.0862 × 10−4a.043a3 × 10−4a.042a5 × 10−4a.019a2 × 10−4a
SpCC.010a10−6a.003a10−6a.001a10−6a.001a10−6a.001a10−6a
TB.505.334.704.490.955.345.432.720.909.502
  • Note:P values are adjusted for multiple comparisons. ATWM indicates anterior temporal WM; BIC, brachium of the inferior colliculus; BoCC, body of the corpus callosum; CST, corticospinal tract; CWM, cerebral WM; DSCP, decussation of the superior cerebellar peduncles; GeCC, genu of the corpus callosum; LL/ML, lateral/medial lemnisci; LGN/MGN, lateral/medial geniculate nuclei; MeyLo, Meyer loop; NAFWM, normal-appearing frontal WM; OR, optic radiations; OT, optic tracts; PLIC, posterior limb of the internal capsule; POWN, parieto-occipital WM; SpCC, splenium of the corpus callosum; TB, trapezoid body.

  • a p < 0.05.