Patient demographics and results

Patient InformationData
Demographics and imagingNo. = 29, male/female = 13:16, mean age = 41 ± 18 yr, range = 11–83 yr;a
    characteristicsleft/right = 9:21 lesions
DTI ADC = 24 patients, DWI ADC = 21 patients
No. of directions in DTI: 14 patients with 12, 10 patients with 20 directions, respectively
Benign and malignant lesionsBenign = 25, malignant = 5
No difference in terms of age (benign = 40 ± 18 versus malignant = 45 ± 19 yr), sex (benign, male/female = 12:13 versus malignant, male/female = 3:2) (P > .05), FA and ADC values (P >0.05);a
DTI ADC different (P = .001), benign = 1.848 ± 0.40 versus malignant = 0.900 ± 0.25 × 10−3 mm2/s;a
DWI ADC not different (P > .05), benign = 1.745 ± 0.44 vs malignant = 1.267 ± 0.35 × 10−3 mm2/s;a
Interobserver reliability ADC: ICC = 0.988 (95% CI, 0.976–0.994), excellenta
Abnormal and contralateral normalFA significantly different (P < .001), abnormal = 0.221 ± 0.09, normal = 0.344 ± 0.12;a
    nervesInterobserver reliability FA: ICC = 0.970 (95% CI, 0.946–0.991), excellenta
DTI ADC among benign lesions between different (12 and 20) directionsNot statistically different (P > .05)
DTI ADC on 12 directions: 1.627 ± 0.600
DTI ADC on 20 directions: 1.520 ± 0.390
DTI ADC and DWI ADCNot statistically different (P > .05)
ICC = 0.943 (95% CI, 0.836–0.980), excellent intermethod reliability
Very good Pearson correlation (r = 0.90, P < .001)