Characteristics | Control Mean | Control SD | MCI Mean | MCI SD | AD Mean | AD SD |
---|---|---|---|---|---|---|
No. | 18 | 18 | 18 | |||
Age (yr) | 71.61 | 9.2 | 70.83 | 10.1 | 70.39 | 9.9 |
Education | 12.78 | 3.11 | 11.28 | 1.99 | 11.00 | 3.30 |
Men/women | 9: 9 | 9: 9 | 9: 9 | |||
MRI TIV/GM ratio (GM fraction) | 2.61 | 0.28 | 2.82 | 0.42 | 2.86 | 0.43 |
MMSE (30) | 29.50 | 0.7 | 28.67 | 1.49 | 24.56b | 3.45 |
CERAD | ||||||
Verbal fluency (24)c | 24.89 | 7.28 | 16.06b | 5.07 | 10.44b | 3.88 |
Modified BNT (15) | 14.56 | 0.78 | 14.50 | 0.99 | 12.33b | 2.50 |
Word list: delayed recall (10) | 8.28 | 1.60 | 6.50b | 2.30 | 2.33b | 1.45 |
Word list: learning (30) | 22.22 | 3.06 | 19.61 | 4.27 | 12.94b | 5.83 |
Constructional praxis (11) | 10.78 | 0.95 | 10.56 | 0.78 | 9.39b | 1.91 |
Constructional praxis: delayed recall (11) | 9.83 | 2.15 | 9.39 | 2.06 | 4.28b | 3.44 |
CERAD total score (101) | 90.56 | 15.82 | 76.62b | 15.47 | 51.71b | 19.01 |
Note:—BNT indicates Boston Naming Test; TIV, total intracranial volume; GM, gray matter; MMSE, Mini-Mental State Examination.
↵a Maximum scores of test subunits are in brackets
↵b One-way ANOVA (P < .05).
↵c Verbal fluency does not have a ceiling when administered using standard instructions as part of the CERAD. For calculation, a cap of 24 was placed on verbal fluency, which represents 1 SD above the normal aging population mean.