Demographic and clinical characteristics of the study group

Hypothermia (n = 18)Healthy Control (n = 18)P Value
Birth weight, kga3.26 ± 0.683.52 ± 0.36.176
Gestational age, weeksa38.8 ± 1.539.5 ± 1.5.163
Sex, n (% male)9 (50)8 (44).738
Apgar scores
    1 minute2 (0–6)8 (3–9)<.001
    5 minutes4 (1–9)9 (8–9)<.001
    10 minutesb5 (2–8)n/a
Initial pHc7.03 (6.74–7.35)n/a
Encephalopathy grade, n (%)
    Moderate15 (83)
    Severe3 (17)
EEG at 18–24 hoursd
    Burst suppression2 (12)
    Discontinuous13 (76)
    Continuous2 (12)
EEG after rewarming
    Discontinuous8 (50)
    Continuous8 (50)
Electrographic seizure4 (22)
MRI day of life9 (7–13)11 (7–22).086

  • Data are presented as median (range) except where noted.

  • ↵a Mean ± SD.

  • ↵b Documented for 14 of 18 patients.

  • ↵c Documented for 17 of 18 patients.

  • ↵d Data available for 17 of 18 patients.