Table 3:

The mean of DKI measures for the 2 groups, based on the median EDSS scorea

MeasureLocationGroup 1 (n = 11)Group 2 (n = 8)P Valueb
FAWC0.54 ± 0.040.49 ± 0.06.002
GM0.74 ± 0.190.65 ± 0.22.01
WM0.53 ± 0.090.50 ± 0.09.1
MDWC0.92 ± 0.090.95 ± 0.09.001
GM0.70 ± 0.210.75 ± 0.23.001
WM0.96 ± 0.151.03 ± 0.14.5
MKWC1.07 ± 0.111.06 ± 0.10.01
GM1.13 ± 0.131.10 ± 0.09<.0001
WM1.09 ± 0.151.08 ± 0.14.3
  • Note:—FA indicates fractional anisotropy; MD, mean diffusivity; WC, whole cord.

  • a Group 1: EDSS score ≤ 2.5; group 2: EDSS score ≥ 3.0.

  • b P values are from ANCOVA, comparing groups 1 and 2 in terms of the indicated DKI measure adjusted for age, sex, and disease duration.