Table 2:

Difference of least square means in perfusion parameters between reference dataset and noise datasets across all ROIs in all participants and across ROIs in participants with perfusion abnormalities (subanalysis)

Perfusion ParameterSimulated Exposure (mAs)All ROIsOnly in ROIs with Perfusion Abnormalities
Difference from Reference DatasetStandard ErrorPAdj PDifference from Reference DatasetStandard ErrorPAdj P
CBF (mL/100 g/min)188−0.120.68.87>.99−0.350.86.69>.99
177−0.200.68.77>.99−0.220.86.80>.99
167−0.720.68.29.73−0.670.86.44.90
127−0.600.68.38.85−0.010.86.99>.99
44−1.810.68.01.040.470.86.58.97
CBV (mL/100 g/min)1880.000.02.89>.99−0.010.02.74>.99
1770.000.02.91>.990.000.02.99>.99
1670.000.02.92>.990.000.02.93>.99
1270.020.02.26.680.010.02.62.98
440.070.02<.0001<.0010.100.02<.0001<.0001
MTT (sec)1880.000.06.94>.990.030.10.79>.99
1770.020.06.74>.990.050.10.66>.99
1670.060.06.32.780.070.10.47.92
1270.110.06.08.280.070.10.51.95
440.460.06<.0001<.0010.330.10.00.01
  • Note:—ROIs with perfusion abnormalities were identified by a trained neuroradiologist (P.S.) with 12 years of experience.

  • Adj P indicates adjusted P value.