Summary of patient characteristics, histopathologic findings, tumor volume and enhancement, microvessel density, and intra- and postoperative hemorrhages in 11 patients with nonfunctioning pituitary macroadenomas

Case/Age (yr)/SexInitial/RecurrenceHistopathologyTumor Volume (cm)Degree of Enhancement of TumorASL-PI nTBFASL-PI TBF (mL/min/100 g)CD-31 %VesselIntraoperative Vascularity FindingsPostoperative Hemorrhage
1/72/MInitialSGA11.41.481.9494.424.0(+)(+)a
2/52/MRecurrenceNCA8.71.500.4729.51.3(−)(−)
3/63/MInitialSGA4.71.360.9622.70.7(−)(−)
4/48/FRecurrenceSGA2.21.440.7551.01.7(−)(−)
5/54/MInitialSGA6.01.711.8874.217.0(+)(+)
6/69/MRecurrenceNCA7.71.810.7226.62.6(−)(−)
7/60/FInitialNCA2.81.270.5138.01.1(−)(−)
8/34/FInitialSGA4.91.880.7359.51.2(−)(−)
9/68/MRecurrenceNCA3.41.820.7626.62.6(−)(−)
10/60/FInitialNCA9.91.682.45102.619.0(+)(+)
11/67/MRecurrenceSGA4.71.961.0346.26.4(−)(−)
  • Note:—SGA indicates gonadotroph adenoma; NCA, null cell adenoma; ASL-PI nTBF, tumor blood flow normalized to the cerebellum measured with ASL-PI; ASL-PI TBF, absolute tumor blood flow (milliliters per minute per 100 g) measured with ASL-PI; (−), hypovascular; +, hypervascular.

  • a Symptomatic hemorrhage.