Table 2:

ANCOVA pos hoc and AUC results of the WMTI metrics of each corpus callosum ROI and the FA skeleton

ROINC (n = 15)aMCI (n = 12)AD (n = 14)NC vs aMCIaMCI vs ADNC vs AD
Mean ± SDMean ± SDMean ± SDP ValueAUCP ValueAUCP ValueAUC
AWFGenu0.35 ± 0.030.33 ± 0.030.32 ± 0.05.250.75.430.67.01a,b0.78
Body0.35 ± 0.030.33 ± 0.030.32 ± 0.04.330.71.350.65.01a,b0.76
Splenium0.41 ± 0.030.39 ± 0.030.35 ± 0.06.360.69.02a0.79<.01c,b0.88
Skeleton0.39 ± 0.020.38 ± 0.020.36 ± 0.04.930.64.01a,b0.84<.01d,b0.83
DaxonGenu1.09 ± 0.061.09 ± 0.051.10 ± 0.091.000.66.880.53.880.53
Body1.22 ± 0.101.18 ± 0.071.19 ± 0.10.650.64.980.54.750.56
Splenium1.20 ± 0.091.17 ± 0.051.15 ± 0.12.820.63.620.71.250.71
Skeleton0.96 ± 0.050.95 ± 0.040.93 ± 0.071.000.66.570.77.490.68
De,‖Genu2.90 ± 0.133.06 ± 0.073.10 ± 0.17.01a,b0.86.570.60<.01c,b0.85
Body2.83 ± 0.113.01 ± 0.102.99 ± 0.15<.01d,b0.89.930.54<.01d,b0.79
Splenium2.79 ± 0.112.93 ± 0.112.95 ± 0.11.01a,b0.82.780.57<.01d,b0.88
Skeleton2.30 ± 0.072.39 ± 0.042.40 ± 0.07<.01c,b0.95.880.53<.01c,b0.92
De,⊥Genu1.33 ± 0.111.52 ± 0.161.58 ± 0.27.01a,b0.91.300.64<.01c,b0.91
Body1.43 ± 0.101.58 ± 0.121.62 ± 0.22.03a0.88.490.63<.01c,b0.80
Splenium1.15 ± 0.101.29 ± 0.121.43 ± 0.25.060.87<.01d,b0.77<.01c,b0.93
Skeleton1.06 ± 0.071.15 ± 0.071.20 ± 0.16.04a0.89.060.77<.0c,b0.89
  • Note:—AUC indicates area under the receiver operating characteristic curve.

  • a P < .05.

  • b P values indicate that the difference remains significant after applying a Bonferroni correction for multiple ROI comparisons.

  • c P < .001.

  • d P < .01.