Demographic data for participants with longitudinal structural and clinical measures
| Diagnostic Group | ε4− | ε4+ | ||||||
|---|---|---|---|---|---|---|---|---|
| Male | Female | Male | Female | |||||
| N | Age, y (SD) | N | Age, y (SD) | N | Age, y (SD) | N | Age, y (SD) | |
| HC | 70 | 75.87 (4.63) | 67 | 76.84 (4.94) | 26 | 76.63 (5.42) | 25 | 75.67 (3.13) |
| MCIa | 74 | 78.52 (5.96) | 42 | 78.70 (4.08) | 102 | 76.07 (5.42) | 55 | 73.64 (5.34) |
| MCIcb | 23 | 78.53 (5.50) | 12 | 78.95 (3.81) | 45 | 75.51 (5.28) | 30 | 72.76 (4.97) |
| ADc | 13 | 75.51 (5.70) | 13 | 78.52 (4.21) | 42 | 75.52 (5.90) | 37 | 75.09 (5.07) |
Note:—N indicates number of participants. Values are mean (standard deviation, SD). MCIc = MCI converters to AD.
↵a MCI: ε4+ women are significantly younger than all other groups (all P < .01); ε4+ men are significantly younger than ε4− men and ε4− women (P < .01).
↵b MCIc: ε4+ women are significantly younger than all other groups (all P < .05); ε4+ men are significantly younger than ε4− men and ε4− women (P < .05).
↵c AD: ε4+ women are significantly younger than ε4− women (P < .05).