Table 1:

Summary of demographics for patients with SMART

Patient	Radiation Indication	Interval, y	Age at Diagnosis, y	Seizures Before	Seizure With	Headache Before	Headache With	Therapies Used
1	Pituitary lesion	22	60	?	Y	N	N	Phenytoin, levetiracetam
2	Pineal tumor	30	42	Y	N	?	Y	Corticosteroids
3	Astrocytoma	32	44	N	N	?	Y	Verapamil, phenytoin
4	Oligoastrocytoma	14	53	Y	Y	N	N	Phenytoin, levetiracetam
5	Dysgerminoma	19	50	N	N	Y	Y	Corticosteroids
6	Fibrillary astrocytoma	13	45	Y	Y	N	N	Levetiracetam, valproate, corticosteroids
7	Astroblastoma	27	58	Y	N	N	Y	Phenytoin, aspirin
8	Lymphoma	16	37	N	Y	Y	Y	Levetiracetam, verapamil, aspirin
9	Oligoastrocytoma	10	50	N	Y	Y	Y	Levetiracetam, verapamil, corticosteroids
10	Metastatic melanoma	6	50	Y	Y	N	Y	Levetiracetam, verapamil, corticosteroids
11	Brain stem glioma	30	58	N	Y	Y	Y	Levetiracetam, verapamil

Note:—“Interval” indicates the interval in years between radiotherapy and the diagnosis of SMART. “Seizures before” and “Seizure with,” “Headache before” and “Headache with” refer to symptoms preceding initiation and during SMART episodes, respectively.