Table 2:

Diagnostic performance of the Cho/Cr ratio, Cho/NAA ratio, and lip-lac grade

P ValueaAUCCutoff ValueSensitivity (%)Specificity (%)
Comparison of all PCNSLs and TDLs
    Cho/Cr ratio.0000.849 (0.739, 0.926)2.5875.0 (59.7, 86.8)81.0 (58.1, 94.4)
    Cho/NAA ratio.0000.885 (0.782, 0.951)1.7388.6 (75.4, 96.2)76.2 (52.8, 91.7)
    Lip-lac grade.0000.801 (0.684, 0.890)347.7 (32.5, 63.3)95.2 (76.2, 99.9)
Comparison of atypical PCNSLs and TDLs
    Cho/Cr ratio.0030.785 (0.628, 0.897)2.3970.0 (45.7, 88.0)71.4 (47.8, 88.6)
    Cho/NAA ratio.0010.883 (0.744, 0.962)1.7390.0 (68.3, 98.5)76.2 (52.8, 91.7)
    Lip-lac grade.0050.745 (0.585, 0.868)335.0 (15.4, 59.2)95.2 (76.2, 99.9)
  • Note:—Numbers in parentheses are the 95% confidence intervals.

  • a P values represent comparison results of PCNSLs and TDLs by use of the Student t test for the Cho/Cr ratio, the Cho/NAA ratio, and the Mann-Whitney U test for the lip-lac grade.