Table 1:

Tumor pathology with corresponding WHO grade and ADC values from manual ROI measurement

Tumor Type	WHO Grade	Average Minimum ADC × 10⁻³ mm²/s	ADC Ratio Thalamus	ADC Ratio White Matter
Desmoplastic infantile ganglioglioma	I	1.63	1.68	1.50
Desmoplastic infantile ganglioglioma	I	0.88	1.05	0.79
Desmoplastic infantile ganglioglioma	I	0.97	1.08	0.80
Desmoplastic infantile ganglioglioma	I	1.14	0.87	0.76
Choroid plexus papilloma	I	1.01	1.05	1.10
Choroid plexus papilloma	I	0.92	1.16	0.79
Choroid plexus papilloma	I	1.31	1.53	1.23
Pilocytic astrocytoma	I	0.78	0.96	0.75
Astrocytoma, focal	II	1.71	1.50	1.35
Pilomyxoid astrocytoma	II	1.03	1.06	0.71
Astrocytoma, diffuse	II	1.12	1.27	0.98
Anaplastic ependymoma	III	0.69	0.82	0.59
Anaplastic ependymoma with tanycytic features	III	0.54	0.57	0.47
Choroid plexus carcinoma	III	1.27	0.93	0.90
Atypical teratoid/rhabdoid tumor	IV	0.67	0.53	0.41
Atypical teratoid/rhabdoid tumor	IV	0.40	0.55	0.42
Poorly differentiated carcinoma	IV	0.56	0.45	0.32
Poorly differentiated carcinoma	IV	0.40	0.51	0.35
Glioblastoma	IV	0.58	0.62	0.41
P value, t test between low- and high-grade groups		.0018	<.0001	.00042

Note:—All 3 parameters were significant between the difference of the means of the low-grade and high-grade groups. Of note, the choroid plexus carcinoma in our study is an outlier in the high-grade group.