Table 1:

Tumor pathology with corresponding WHO grade and ADC values from manual ROI measurement

Tumor TypeWHO GradeAverage Minimum ADC × 10−3 mm2/sADC Ratio ThalamusADC Ratio White Matter
Desmoplastic infantile gangliogliomaI1.631.681.50
Desmoplastic infantile gangliogliomaI0.881.050.79
Desmoplastic infantile gangliogliomaI0.971.080.80
Desmoplastic infantile gangliogliomaI1.140.870.76
Choroid plexus papillomaI1.011.051.10
Choroid plexus papillomaI0.921.160.79
Choroid plexus papillomaI1.311.531.23
Pilocytic astrocytomaI0.780.960.75
Astrocytoma, focalII1.711.501.35
Pilomyxoid astrocytomaII1.031.060.71
Astrocytoma, diffuseII1.121.270.98
Anaplastic ependymomaIII0.690.820.59
Anaplastic ependymoma with tanycytic featuresIII0.540.570.47
Choroid plexus carcinomaIII1.270.930.90
Atypical teratoid/rhabdoid tumorIV0.670.530.41
Atypical teratoid/rhabdoid tumorIV0.400.550.42
Poorly differentiated carcinomaIV0.560.450.32
Poorly differentiated carcinomaIV0.400.510.35
P value, t test between low- and high-grade groups.0018<.0001.00042
  • Note:—All 3 parameters were significant between the difference of the means of the low-grade and high-grade groups. Of note, the choroid plexus carcinoma in our study is an outlier in the high-grade group.